Gambar profil Chemist7231
@Chemist7231
Bendera Pakistan Karachi, Pakistan
Anggota sejak 11 Januari 2015
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Chemist7231

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I have completed Ph.D. in chemistry. I have worked on synthesis of organic molecules and biotransformation of natural as well synthetic compounds. I have two year teaching experience of under graduate classes. As I am working on biotransformation of compounds, therefore I have extensive experience of specteral elucidation of compounds by using various spectroscopic techniques. I can help the student in various field of chemistry. I am expert in UV, IR, NMR, 2DNMR, spectroscopy and Mass spectrometry.
$10 USD/jam
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Ulasan Terbaru

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Pengalaman

Research Officer

Jan 2013 - Jan 2014 (1 year)

Work on Bio-transformation of steroids.

Pendidikan

Ph.D

2010 - 2015 (5 years)

Kualifikasi

GRE chemistry (2011)

ETS

Passed GRE chemistry with 60 percentile

Publikasi

Biotransformation of androgenic steroid mesterolone with Cunninghamella blakesleeana and Macrophomina phaseolina

Fermentation of mesterolone (1) with Cunninghamella blakesleeana yielded four new metabolites, 1a-methyl-1b,11b,17b-trihydroxy-5a-androstan-3-one (2), 1a-methyl-7a,11b,17b-trihydroxy-5a-androstan- 3-one (3), 1a-methyl-1b,6a,17b-trihydroxy-5a-androstan-3-one (4) and 1a-methyl-1b,11a,17b-trihydroxy- 5a-androstan-3-one (5), along with three known metabolites, 1a-methyl-11a,17b-dihydroxy- 5a-androstan-3-one (6), 1a-methyl-6a,17b-dihydroxy-5a-androstan-3-one (7) and 1a-methyl-7a,17bdihydroxy- 5a-androstan-3

Microbial transformation of nandrolone with Cunninghamella echinulata and Cunninghamella blakesleeana and evaluation of leishmaniacidal activity of transformed products

Therapeutic potential of nandrolone and its derivatives against leishmaniasis has been studied. A number of derivatives of nandrolone (1) were synthesized through biotransformation. Microbial transformation of nandrolone (1) with Cunninghamella echinulata and Cunninghamella blakesleeana yielded three new metabolites, 10b,12b,17b-trihydroxy-19-nor-4-androsten-3-one (2), 10b,16a,17b-trihydroxy-19-nor-4- androsten-3-one (3), and 6b,10b,17b-trihydroxy-19-nor-4-androsten-3-one (4), along with four known met

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