I have experience monetizing websites with multiple ad networks, exchanges and SSPs. I have used OpenX, Google AdExchange, Liverail, Criteo and many other ad tags and generated revenue by setting up waterfall models (pass back). However, I have not worked with Pulsepoint and Pubmatic.
Optimizing a website for CPM and fill rate to generate revenue, might or might not take more than 4 weeks depending on various parameters like website niche, traffic source and quality (paid or organic), consistency and volume.
Please let me know if you have a developer to implement ad tags or if it is done using an ad server like DFP.